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Altogether, virus is isolated from more than 20 mosquito species, mainly in the genus Aedes.

Sporadic human cases are identified, mostly by serological methods, but such cases are rare, and the disease is regarded as benign.

Although wind-blown mosquitoes can travel distances of several hundred kilometres over the open ocean, introduction of the virus by travel or trade involving an infected person or an infected mosquito is considered the most likely source of this outbreak, especially as no monkeys were present on the island during the outbreak.

The finding on Yap Island that Zika virus can cause an outbreak numbering more than one hundred confirmed and probable cases is striking.

Two geographically distinct lineages of the virus, African and Asian, are identified.

Analysis of virus from Yap Island strengthens previous epidemiological evidence that the outbreak on Yap Island originated in south-east Asia.

Zika, a flavivirus transmitted mainly by mosquitos in the genus Aedes, was discovered in 1947 in Uganda.

The results of retrospective investigations are reported to WHO on 24 November 2015 and 27 January 2016.

Please note: This document is a historical rendering of the Zika virus disease up until 7 February 2016.

WHO continuously adds to Zika virus: News and updates with the latest information available on this public health emergency.

Though a pink non-itchy rash lasting 5 days eventually covers most of his body, including the palms of his hands and soles of his feet, he reports his illness as “mild”, as he did not experience the “crippling bone pain” associated with dengue and chikungunya infections.

Given the mild nature of the illness, the author concludes that “it is not surprising under normal circumstances the virus is not isolated frequently from man.”1960s-1980s: Zika is now being detected in mosquitos and sentinel rhesus monkeys used for field research studies in a narrow band of countries that stretch across equatorial Africa.

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